A real-world pharmacovigilance study on cardiovascular adverse events of tisagenlecleucel using machine learning approach
Abstract Chimeric antigen receptor T-cell (CAR-T) therapies are a paradigm-shifting therapeutic in patients with hematological malignancies. However, some concerns remain that they may cause serious cardiovascular adverse events (AEs), for which data are scarce. In this study, gradient boosting mach...
| Main Authors: | , , , , , |
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| 格式: | 文件 |
| 语言: | English |
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Nature Portfolio
2024-06-01
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| 丛编: | Scientific Reports |
| 主题: | |
| 在线阅读: | https://doi.org/10.1038/s41598-024-64466-x |