c-Myc Suppression of DNA Double-strand Break Repair

c-Myc Suppression of DNA Double-strand Break Repair

c-Myc is a transcriptional factor that functions as a central regulator of cell growth, proliferation, and apoptosis. Overexpression of c-Myc also enhances DNA double-strand breaks (DSBs), genetic instability, and tumorigenesis. However, the mechanism(s) involved remains elusive. Here, we discovered...

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Bibliographic Details
Main Authors: Zhaozhong Li, Taofeek K. Owonikoko, Shi-Yong Sun, Suresh S. Ramalingam, Paul W. Doetsch, Zhi-Qiang Xiao, Fadlo R. Khuri, Walter J. Curran, Xingming Deng
Format: Article
Language:English
Published: Elsevier 2012-12-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558612800558

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http://www.sciencedirect.com/science/article/pii/S1476558612800558

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