Melatonin alleviates particulate matter-induced liver fibrosis by inhibiting ROS-mediated mitophagy and inflammation via Nrf2 activation

Melatonin alleviates particulate matter-induced liver fibrosis by inhibiting ROS-mediated mitophagy and inflammation via Nrf2 activation

Objective: Fine particulate matter (PM2.5) is a source of pollution worldwide, that causes inflammation and liver fibrosis. Melatonin, as the predominant hormone secreted by the pineal gland, can inhibit PM2.5-induced lung injury by activating nuclear factor erythroid 2-related factor 2 (Nrf2) to in...

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Bibliographic Details
Main Authors: Laiyu Zhu, Qi Zhang, Cong Hua, Xinxin Ci
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Melatonin
PM2.5
Liver Fibrosis
Nrf2
Mitophagy
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323012216

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http://www.sciencedirect.com/science/article/pii/S0147651323012216

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