Expression and Function of Eicosanoid-Producing Cytochrome P450 Enzymes in Solid Tumors

Expression and Function of Eicosanoid-Producing Cytochrome P450 Enzymes in Solid Tumors

Oxylipins derived from the oxidation of polyunsaturated fatty acids (PUFAs) act as important paracrine and autocrine signaling molecules. A subclass of oxylipins, the eicosanoids, have a broad range of physiological outcomes in inflammation, the immune response, cardiovascular homeostasis, and cell...

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Bibliographic Details
Main Authors: Eric A. Evangelista, Christi W. Cho, Theresa Aliwarga, Rheem A. Totah
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Pharmacology
Subjects:
epoxygenases
hydroxylases
cytochrome P450
epoxyeicosatrienoic acids
hydroxyeicosatetraenoic acids
20-HETE
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00828/full

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https://www.frontiersin.org/article/10.3389/fphar.2020.00828/full

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