A Comprehensive Atlas of Immunological Differences Between Humans, Mice, and Non-Human Primates

Animal models are an integral part of the drug development and evaluation process. However, they are unsurprisingly imperfect reflections of humans, and the extent and nature of many immunological differences are unknown. With the rise of targeted and biological therapeutics, it is increasingly impo...

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Bibliographic Details
Main Authors: Zachary B. Bjornson-Hooper, Gabriela K. Fragiadakis, Matthew H. Spitzer, Han Chen, Deepthi Madhireddy, Kevin Hu, Kelly Lundsten, David R. McIlwain, Garry P. Nolan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.867015/full