Excretory/secretory products from Trichinella spiralis adult worms ameliorate myocardial infarction by inducing M2 macrophage polarization in a mouse model

Excretory/secretory products from Trichinella spiralis adult worms ameliorate myocardial infarction by inducing M2 macrophage polarization in a mouse model

Abstract Background Ischemia-induced inflammatory response is the main pathological mechanism of myocardial infarction (MI)-caused heart tissue injury. It has been known that helminths and worm-derived proteins are capable of modulating host immune response to suppress excessive inflammation as a su...

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Bibliographic Details
Main Authors: Lingqin Wu, Wenhui Yin, Jutai Wen, Shuying Wang, Huihui Li, Xiaoli Wang, Weixiao Zhang, Shuyao Duan, Qiuyu Zhu, Erhe Gao, Shili Wu, Bin Zhan, Rui Zhou, Xiaodi Yang
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Parasites & Vectors
Subjects:
Myocardial infarction
Excretory-secretory products
Trichinella spiralis
Macrophage
Immunomodulation
Online Access:https://doi.org/10.1186/s13071-023-05930-x

Internet

https://doi.org/10.1186/s13071-023-05930-x

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