Decorin: a potential therapeutic candidate for ligamentum flavum hypertrophy by antagonizing TGF-β1

Decorin: a potential therapeutic candidate for ligamentum flavum hypertrophy by antagonizing TGF-β1

Abstract Ligamentum flavum hypertrophy (LFH) is the main physiological and pathological mechanism of lumbar spinal canal stenosis (LSCS). The specific mechanism for LFH has not been completely clarified. In this study, bioinformatic analysis, human ligamentum flavum (LF) tissues collection and analy...

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Bibliographic Details
Main Authors: Shanxi Wang, Yunkun Qu, Xuan Fang, Qing Ding, Hongqi Zhao, Xiaojun Yu, Tao Xu, Rui Lu, Shaoze Jing, Chaoxu Liu, Hua Wu, Yang Liu
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-01023-y

Internet

https://doi.org/10.1038/s12276-023-01023-y

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