Decorin: a potential therapeutic candidate for ligamentum flavum hypertrophy by antagonizing TGF-β1

Abstract Ligamentum flavum hypertrophy (LFH) is the main physiological and pathological mechanism of lumbar spinal canal stenosis (LSCS). The specific mechanism for LFH has not been completely clarified. In this study, bioinformatic analysis, human ligamentum flavum (LF) tissues collection and analy...

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Main Authors: Shanxi Wang, Yunkun Qu, Xuan Fang, Qing Ding, Hongqi Zhao, Xiaojun Yu, Tao Xu, Rui Lu, Shaoze Jing, Chaoxu Liu, Hua Wu, Yang Liu
格式: 文件
语言:English
出版: Nature Publishing Group 2023-07-01
丛编:Experimental and Molecular Medicine
在线阅读:https://doi.org/10.1038/s12276-023-01023-y