<i>N</i>-Butyrylated Hyaluronic Acid Achieves Anti-Inflammatory Effects In Vitro and in Adjuvant-Induced Immune Activation in Rats

<i>N</i>-Butyrylated Hyaluronic Acid Achieves Anti-Inflammatory Effects In Vitro and in Adjuvant-Induced Immune Activation in Rats

Previously synthesized <i>N</i>-butyrylated hyaluronic acid (BHA) provides anti-inflammatory effects in rat models of acute gouty arthritis and hyperuricemia. However, the mechanism of action remains to be elucidated. Herein, the anti-inflammatory and antioxidative activities of BHA and...

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Bibliographic Details
Main Authors: Xue Luan, Zhongcheng Cong, Tassos P. Anastassiades, Yin Gao
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Molecules
Subjects:
<i>N</i>-butyrylation
anti-inflammation
antioxidation
NF-κB/MAPK
JAK-STAT
Online Access:https://www.mdpi.com/1420-3049/27/10/3267

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https://www.mdpi.com/1420-3049/27/10/3267

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