Q192R Paraoxonase (PON)1 Polymorphism, Insulin Sensitivity, and Endothelial Function in Essential Hypertensive Men

Aims Essential hypertension is characterized by increased reactive oxygen species (ROS) generation harmful for insulin sensitivity and nitric oxide (NO)-mediated vasomotor function, a noxious effect that paraoxonase ( PON )l, an antioxidant circulating high-density lipoprotein (HDL)-bound esterase,...

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Bibliographic Details
Main Authors: Giulia Dell'omo, Giuseppe Penno, Laura Pucci, Daniela Lucchesi, Stefano Del Prato, Roberto Pedrinelli
Format: Article
Language:English
Published: SAGE Publishing 2014-01-01
Series:Clinical Medicine Insights: Cardiology
Online Access:https://doi.org/10.4137/CMC.S15493