Cellular senescence of renal tubular epithelial cells in acute kidney injury

Abstract Cellular senescence represents an irreversible state of cell-cycle arrest during which cells secrete senescence-associated secretory phenotypes, including inflammatory factors and chemokines. Additionally, these cells exhibit an apoptotic resistance phenotype. Cellular senescence serves a p...

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Bibliographic Details
Main Authors: Juan Chen, Huhai Zhang, Xiangling Yi, Qian Dou, Xin Yang, Yani He, Jia Chen, Kehong Chen
Format: Article
Language:English
Published: Nature Publishing Group 2024-02-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-01831-9