The fate of a designed protein corona on nanoparticles in vitro and in vivo

The fate of a designed protein corona on nanoparticles in vitro and in vivo

A variety of monodisperse superparamagnetic iron oxide particles (SPIOs) was designed in which the surface was modified by PEGylation with mono- or bifunctional poly(ethylene oxide)amines (PEG). Using 125I-labeled test proteins (transferrin, albumin), the binding and exchange of corona proteins was...

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Bibliographic Details
Main Authors: Denise Bargheer, Julius Nielsen, Gabriella Gébel, Markus Heine, Sunhild C. Salmen, Roland Stauber, Horst Weller, Joerg Heeren, Peter Nielsen
Format: Article
Language:English
Published: Beilstein-Institut 2015-01-01
Series:Beilstein Journal of Nanotechnology
Subjects:
albumin
59Fe
125I
organ uptake
protein corona
SPIOs
transferrin
Online Access:https://doi.org/10.3762/bjnano.6.5

Internet

https://doi.org/10.3762/bjnano.6.5

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