The fate of a designed protein corona on nanoparticles in vitro and in vivo
A variety of monodisperse superparamagnetic iron oxide particles (SPIOs) was designed in which the surface was modified by PEGylation with mono- or bifunctional poly(ethylene oxide)amines (PEG). Using 125I-labeled test proteins (transferrin, albumin), the binding and exchange of corona proteins was...
Main Authors: | Denise Bargheer, Julius Nielsen, Gabriella Gébel, Markus Heine, Sunhild C. Salmen, Roland Stauber, Horst Weller, Joerg Heeren, Peter Nielsen |
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Format: | Article |
Language: | English |
Published: |
Beilstein-Institut
2015-01-01
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Series: | Beilstein Journal of Nanotechnology |
Subjects: | |
Online Access: | https://doi.org/10.3762/bjnano.6.5 |
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