Development of Neuronal Guidance Fibers for Stimulating Electrodes: Basic Construction and Delivery of a Growth Factor

Development of Neuronal Guidance Fibers for Stimulating Electrodes: Basic Construction and Delivery of a Growth Factor

State-of-the-art treatment for sensorineural hearing loss is based on electrical stimulation of residual spiral ganglion neurons (SGNs) with cochlear implants (CIs). Due to the anatomical gap between the electrode contacts of the CI and the residual afferent fibers of the SGNs, spatial spreading of...

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Bibliographic Details
Main Authors: Inga Wille, Jennifer Harre, Sarah Oehmichen, Maren Lindemann, Henning Menzel, Nina Ehlert, Thomas Lenarz, Athanasia Warnecke, Peter Behrens
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
cochlea implant
implant-associated drug delivery
BDNF
heparan sulfate
polycaprolactone
polyglycolide
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.776890/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.776890/full

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