Administration of Tamoxifen Can Regulate Changes in Gene Expression during the Acute Phase of Traumatic Spinal Cord Injury

Administration of Tamoxifen Can Regulate Changes in Gene Expression during the Acute Phase of Traumatic Spinal Cord Injury

Traumatic spinal cord injury (SCI) causes irreversible damage leading to incapacity. Molecular mechanisms underlying SCI damage are not fully understood, preventing the development of novel therapies. Tamoxifen (TMX) has emerged as a promising therapy. Our aim was to identify transcriptome changes i...

Full description

Bibliographic Details
Main Authors: Eibar E. Cabrera-Aldana, Yalbi I. Balderas-Martinez, Rafael Velázquez-Cruz, Luis B. Tovar-y-Romo, Rosalba Sevilla-Montoya, Angelina Martínez-Cruz, Claudia Martinez-Cordero, Margarita Valdes-Flores, Monica Santamaria-Olmedo, Alberto Hidalgo-Bravo, Gabriel Guízar-Sahagún
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Current Issues in Molecular Biology
Subjects:
spinal cord injury
transcriptome
tamoxifen
gene expression
inflammatory response
Online Access:https://www.mdpi.com/1467-3045/45/9/472

Internet

https://www.mdpi.com/1467-3045/45/9/472

Similar Items