18F-FP-PEG2-β-Glu-RGD2: A Symmetric Integrin αvβ3-Targeting Radiotracer for Tumor PET Imaging.

Radiolabeled cyclic arginine-glycine-aspartic (RGD) peptides can be used for noninvasive determination of integrin αvβ3 expression in tumors. In this study, we performed radiosynthesis and biological evaluation of a new 18F-labeled RGD homodimeric peptide with one 8-amino-3,6-dioxaoctanoic acid (PEG...

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Bibliographic Details
Main Authors: Kongzhen Hu, Xiaolan Tang, Ganghua Tang, Shaobo Yao, Baoguo Yao, Hongliang Wang, Dahong Nie, Xiang Liang, Caihua Tang, Shanzhen He
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4580323?pdf=render