<i>Salmonella enterica</i>’s “Choice”: Itaconic Acid Degradation or Bacteriocin Immunity Genes

Itaconic acid is an immunoregulatory metabolite produced by macrophages in response to pathogen invasion. It also exhibits antibacterial activity because it is an uncompetitive inhibitor of isocitrate lyase, whose activity is required for the glyoxylate shunt to be operational. Some bacteria, such a...

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Bibliographic Details
Main Author: Rolf D. Joerger
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/11/7/797