Formosanin C induces autophagy-mediated apoptosis in multiple myeloma cells through the PI3K/AKT/mTOR signaling pathway

Formosanin C induces autophagy-mediated apoptosis in multiple myeloma cells through the PI3K/AKT/mTOR signaling pathway

Objectives Multiple myeloma (MM) is an incurable plasma cell malignancy associated with poor survival. Novel therapeutic drugs are urgently needed to improve MM therapy and patient outcomes. This study aimed to investigate the effect of formosanin C (FC), a Chinese medicine monomer, on MM in vitro a...

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Bibliographic Details
Main Authors: Ping Chen, Sungui Wu, Xiaoqing Dong, Min Zhou, Peipei Xu, Bing Chen
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Hematology
Subjects:
Formosanin C
multiple myeloma
autophagy
apoptosis
PI3K/AKT/mTOR
Online Access:https://www.tandfonline.com/doi/10.1080/16078454.2022.2117126

Internet

https://www.tandfonline.com/doi/10.1080/16078454.2022.2117126

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