HIV-1 Tat protein enhances Microtubule polymerization

<p>Abstract</p> <p>Background</p> <p>HIV infection and progression to AIDS is characterized by the depletion of T cells, which could be due, in part, to apoptosis mediated by the extra-cellular HIV-encoded Tat protein as a consequence of Tat binding to tubulin. Microtub...

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Bibliographic Details
Main Authors: Prevot Charles, Watkins Jennifer D, Esquieu Didier, Opi Sandrine, Lancelot Sophie, Campbell Grant R, Barbier Pascale, Carre Manon, de Mareuil Jean, Braguer Diane, Peyrot Vincent, Loret Erwann P
Format: Article
Language:English
Published: BMC 2005-02-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/2/1/5