The HMOX2 polymorphism contributes to the carotid body chemoreflex in European sea-level residents by regulating hypoxic ventilatory responses

The HMOX2 polymorphism contributes to the carotid body chemoreflex in European sea-level residents by regulating hypoxic ventilatory responses

This study investigates whether a functional single nucleotide polymorphism of HMOX2 (heme oxygenase-2) (rs4786504 T>C) is involved in individual chemosensitivity to acute hypoxia, as assessed by ventilatory responses, in European individuals. These responses were obtained at rest and during...

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Bibliographic Details
Main Authors: Pierre Fabries, Catherine Drogou, Fabien Sauvet, Olivier Nespoulous, Marie-Claire Erkel, Vincent Marchandot, Walid Bouaziz, Benoît Lepetit, Anne-Pia Hamm-Hornez, Alexandra Malgoyre, Nathalie Koulmann, Danielle Gomez-Merino, Mounir Chennaoui
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Medicine
Subjects:
acute hypoxia
exercise
chemosensitivity
heme oxygenase-2
genetics
individual vulnerability
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.1000786/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.1000786/full

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