Gut microbiota regulates postprandial GLP-1 response via ileal bile acid-TGR5 signaling

Gut microbiota regulates postprandial GLP-1 response via ileal bile acid-TGR5 signaling

ABSTRACTThe gut microbiota interacts with intestinal epithelial cells through microbial metabolites to regulate the release of gut hormones. We investigated whether the gut microbiota affects the postprandial glucagon-like peptide-1 (GLP-1) response using antibiotic-treated mice and germ-free mice....

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Bibliographic Details
Main Authors: Qiaoling Wang, Huibin Lin, Chongrong Shen, Minchun Zhang, Xingyu Wang, Miaomiao Yuan, Mingyang Yuan, Sheng Jia, Zhiwen Cao, Chao Wu, Banru Chen, Aibo Gao, Yufang Bi, Guang Ning, Weiqing Wang, Jiqiu Wang, Ruixin Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Gut Microbes
Subjects:
Microbiome
GLP-1
bile acid
TGR5
ileum
diabetes
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2023.2274124

Internet

https://www.tandfonline.com/doi/10.1080/19490976.2023.2274124

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