Impact of Preformed Donor-Specific Anti-HLA-Cw and Anti-HLA-DP Antibodies on Acute Antibody-Mediated Rejection in Kidney Transplantation

Impact of Preformed Donor-Specific Anti-HLA-Cw and Anti-HLA-DP Antibodies on Acute Antibody-Mediated Rejection in Kidney Transplantation

Given the risk of rejection, the presence of preformed donor specific antibodies (DSA) contraindicates transplantation in most allocation systems. However, HLA-Cw and -DP DSA escape this censorship. We performed a multicentric observational study, in which the objective was to determinate risk facto...

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Bibliographic Details
Main Authors: Timothée Laboux, Rémi Lenain, Jonathan Visentin, Gauthier Flahaut, Paul Chamley, François Provôt, Isabelle Top, Clarisse Kerleau, Myriam Labalette, Gabriel Choukroun, Lionel Couzi, Gilles Blancho, Marc Hazzan, Mehdi Maanaoui
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Transplant International
Subjects:
donor-specific antibodies
kidney transplant
acute antibody-mediated rejection
HLA-Cw
HLA-DP
Online Access:https://www.frontierspartnerships.org/articles/10.3389/ti.2023.11416/full

Internet

https://www.frontierspartnerships.org/articles/10.3389/ti.2023.11416/full

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