Therapeutic Effect of Alprostadil in Diabetic Nephropathy: Possible Roles of Angiopoietin-2 and IL-18

Therapeutic Effect of Alprostadil in Diabetic Nephropathy: Possible Roles of Angiopoietin-2 and IL-18

Background/Aims: To investigate the role of angiopoietin-2 (Ang-2) and IL-18 in the pathogenesis of diabetic nephropathy (DN) and the molecular mechanisms through which alprostadil protects renal function. Methods: DN was induced by streptozotocin and intraperitoneal injection of alprostadil was giv...

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Bibliographic Details
Main Authors: Changqing Luo, Ting Li, Chun Zhang, Qing Chen, Zhenqiong Li, Jianshe Liu, Yumei Wang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Angiopoietin-2
IL-18
Glomerular endothelial cells
Diabetic Nephropathy
Alprostadil
Online Access:http://www.karger.com/Article/FullText/366309

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http://www.karger.com/Article/FullText/366309

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