Zinc oxide nanoparticle attenuates chemotherapy resistance by inducing cell stemness progression of colorectal cancer via miR-1321/HIF-2α axis

Zinc oxide nanoparticle attenuates chemotherapy resistance by inducing cell stemness progression of colorectal cancer via miR-1321/HIF-2α axis

Background: Colorectal cancer (CRC) is the most malignant cancer type with high morbidity and mortality worldwide. Developed drug resistance severely affected the prognosis of CRC patients. This work aimed to explore the effects of zinc oxide nanoparticles (ZONs) in chemo-resistant CRC. Methods: We...

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Bibliographic Details
Main Authors: Hua Ye, Kefeng Wu, Yi Liu, Yuzhen Zhu, Hui Luo, Wenying Zou
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Arabian Journal of Chemistry
Subjects:
Colorectal cancer
Zinc oxide nanoparticles
Stemness
miR-1321
HIF-2α
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535222002544

Internet

http://www.sciencedirect.com/science/article/pii/S1878535222002544

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