Cathepsin X Activity Does Not Affect NK-Target Cell Synapse but Is Rather Distributed to Cytotoxic Granules

Cathepsin X Activity Does Not Affect NK-Target Cell Synapse but Is Rather Distributed to Cytotoxic Granules

Cathepsin X is a lysosomal peptidase that is involved in tumour progression and represents a potential target for therapeutic interventions. In addition, it regulates important functions of immune cells and is implicated in the modulation of tumour cell–immune cell crosstalk. Selective cathepsin X i...

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Bibliographic Details
Main Authors: Tanja Jakoš, Mateja Prunk, Anja Pišlar, Janko Kos
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
cytotoxic cells
cathepsin X
NK-92
immunological synapse
LFA-1
Online Access:https://www.mdpi.com/1422-0067/22/24/13495

Internet

https://www.mdpi.com/1422-0067/22/24/13495

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