Alterations of NK Cell Phenotype During Pregnancy in Multiple Sclerosis

Alterations of NK Cell Phenotype During Pregnancy in Multiple Sclerosis

In multiple sclerosis (MS), relapse rate is decreased by 70-80% in the third trimester of pregnancy. However, the underlying mechanisms driving this effect are poorly understood. Evidence suggests that CD56bright NK cell frequencies increase during pregnancy. Here, we analyze pregnancy-related NK ce...

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Bibliographic Details
Main Authors: Anne Wisgalla, Caren Ramien, Mathias Streitz, Stephan Schlickeiser, Andreea-Roxana Lupu, Anke Diemert, Eva Tolosa, Petra C. Arck, Judith Bellmann-Strobl, Nadja Siebert, Christoph Heesen, Friedemann Paul, Manuel A. Friese, Carmen Infante-Duarte, Stefan M. Gold
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
natural killer cells
multiple sclerosis
pregnancy
immune tolerance
immune profiling
FlowSOM clustering
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.907994/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.907994/full

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