Further Probing of Cu<sup>2+</sup>-Dependent PNAzymes Acting as Artificial RNA Restriction Enzymes
Peptide nucleic acid (PNA)-neocuproine conjugates have been shown to efficiently catalyse the cleavage of RNA target sequences in the presence of Cu<sup>2+</sup> ions in a site-specific manner. These artificial enzymes are designed to force the formation of a bulge in the RNA target, the...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2019-02-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/24/4/672 |