Application of Defined Approaches for Skin Sensitization to Agrochemical Products

Application of Defined Approaches for Skin Sensitization to Agrochemical Products

Skin sensitization testing is a regulatory requirement for safety evaluations of pesticides in multiple countries. Globally harmonized test guidelines that include in chemico and in vitro methods reduce animal use, but no single assay is recommended as a complete replacement for animal tests. Define...

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Bibliographic Details
Main Authors: Judy Strickland, James Truax, Marco Corvaro, Raja Settivari, Joseph Henriquez, Jeremy McFadden, Travis Gulledge, Victor Johnson, Sean Gehen, Dori Germolec, David G. Allen, Nicole Kleinstreuer
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Toxicology
Subjects:
adverse outcome pathway
alternatives to animal testing
chemical allergy
defined approaches
new approach methodologies
skin sensitization
Online Access:https://www.frontiersin.org/articles/10.3389/ftox.2022.852856/full

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https://www.frontiersin.org/articles/10.3389/ftox.2022.852856/full

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