ALCAT1-mediated abnormal cardiolipin remodelling promotes mitochondrial injury in podocytes in diabetic kidney disease

ALCAT1-mediated abnormal cardiolipin remodelling promotes mitochondrial injury in podocytes in diabetic kidney disease

Abstract Background Cardiolipin (CL) plays a critical role in maintaining mitochondrial membrane integrity and overall mitochondrial homeostasis. Recent studies have suggested that mitochondrial damage resulting from abnormal cardiolipin remodelling is associated with the pathogenesis of diabetic ki...

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Bibliographic Details
Main Authors: Yiqun Hao, Yanqin Fan, Jun Feng, Zijing Zhu, Zilv Luo, Hongtu Hu, Weiwei Li, Hongxia Yang, Guohua Ding
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Cell Communication and Signaling
Subjects:
ALCAT1
Cardiolipin remodelling
Oxidized cardiolipin
Mitochondrial dysfunction
Podocyte injury
Diabetic kidney disease
Online Access:https://doi.org/10.1186/s12964-023-01399-4

Internet

https://doi.org/10.1186/s12964-023-01399-4

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