First purified recombinant CYP75B including transmembrane helix with unexpected high substrate specificity to (2R)-naringenin

Abstract Anthochlor pigments (chalcones and aurones) play an important role in yellow flower colourization, the formation of UV-honey guides and show numerous health benefits. The B-ring hydroxylation of chalcones is performed by membrane bound cytochrome P450 enzymes. It was assumed that usual flav...

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Bibliographic Details
Main Authors: Johanna Hausjell, Julia Weissensteiner, Christian Molitor, Karin Schlangen, Oliver Spadiut, Heidi Halbwirth
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-11556-3