Alkyl Protocatechuate-Loaded Nanostructured Lipid Systems as a Treatment Strategy for Paracoccidioides brasiliensis and Paracoccidioides lutzii In Vitro

Dodecyl protocatechuate (dodecyl) is a derivative of protocatechuic acid (3,4-dihydroxybenzoic acid) that possesses anti-oxidant and antifungal properties. Nanostructured lipid systems (NLS) can potentiate the action of many antifungal agents, reducing the required dose and side effects by improving...

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Bibliographic Details
Main Authors: Kaila P. Medina-Alarcón, Junya L. Singulani, Aline R. Voltan, Janaina C. O. Sardi, Maicon S. Petrônio, Mariana B. Santos, Carlos R. Polaquini, Luis O. Regasini, Vanderlan S. Bolzani, Dulce H. S. da Silva, Marlus Chorilli, Maria J. S. Mendes-Giannini, Ana M. Fusco-Almeida
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.01048/full