Niosomes modified with a novel pH-responsive coating (mPEG-OA) enhance the antibacterial and anti-biofilm activity of vancomycin against methicillin-resistant Staphylococcus aureus

Niosomes modified with a novel pH-responsive coating (mPEG-OA) enhance the antibacterial and anti-biofilm activity of vancomycin against methicillin-resistant Staphylococcus aureus

Surface functionalization of nanoparticles has shown potential in enhancing the efficacy of antibiotic-loaded nanosystems against drug-resistant bacteria. The objective of this study was to synthesize and characterize an acid-cleavable pH-responsive polymer from methoxy polyethylene glycol and oleyl...

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Bibliographic Details
Main Authors: Nawras Osman, Calvin A Omolo, Mohammed A Gafar, Nikita Devnarain, Sanjeev Rambharose, Usri H Ibrahim, Victoria O Fasiku, Thirumala Govender
Format: Article
Language:English
Published: IOP Publishing 2024-01-01
Series:Nano Express
Subjects:
PEGylated niosomes
oleylamine
methicillin-resistant staphylococcus aureus
pH-responsive
surface modified nanoparticles
vancomycin
Online Access:https://doi.org/10.1088/2632-959X/ad1d02

Internet

https://doi.org/10.1088/2632-959X/ad1d02

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