Development of Fed-Batch Cultivation Strategy for Efficient Oxytetracycline Production by Streptomyces rimosus at Semi-Industrial Scale

Development of Fed-Batch Cultivation Strategy for Efficient Oxytetracycline Production by Streptomyces rimosus at Semi-Industrial Scale

ABSTRACTOxytetracycline (OTC) production byStreptomyces rimosus was studied in batch and fed-batch cultures in shake flask and bioreactor levels using semi-defined medium. First, the effect of glucose concentration on OTC production and growth kinetics was studied intensively. The optimal glucose co...

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Bibliographic Details
Main Authors: Elsayed Ahmed Elsayed, Hoda Gamal Omar, Hesham Ali El-Enshasy
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2015-10-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Oxytetracycline
Streptomyces rimosus
bioreactor
fed-batch cultivation
feed-back control
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000500676&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000500676&lng=en&tlng=en

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