Myricitrin inhibits fibroblast-like synoviocyte-mediated rheumatoid synovial inflammation and joint destruction by targeting AIM2

Objective: To explore the effect and underlying mechanism of Myricitrin (Myr) in regulating fibroblast-like synoviocyte (FLS)-mediated synovitis and joint destruction in RA.Methods: FLSs were isolated from synovial tissues from patients with RA. Gene expression was measured using quantitative RT-qPC...

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Bibliographic Details
Main Authors: Chuyu Shen, Meilin Xu, Siqi Xu, Shuoyang Zhang, Wei Lin, Hao Li, Shan Zeng, Qian Qiu, Liuqin Liang, Youjun Xiao, Hanshi Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.905376/full