Detecting Genetic Variation of Colonizing Streptococcus agalactiae Genomes in Humans: A Precision Protocol

Detecting Genetic Variation of Colonizing Streptococcus agalactiae Genomes in Humans: A Precision Protocol

Deciphering the genotypic diversity of within-individual pathogens and verifying the evolutionary model can help elucidate resistant genotypes, virulent subpopulations, and the mechanism of opportunistic pathogenicity. However, observed polymorphic mutations (PMs) are rare and difficult to be detect...

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Bibliographic Details
Main Authors: Yan Zhou, Xue-Chao Zhao, Lin-Qi Wang, Cheng-Wen Chen, Mei-Hua Hsu, Wan-Ting Liao, Xiao Deng, Qing Yan, Guo-Ping Zhao, Chyi-Liang Chen, Liang Zhang, Cheng-Hsun Chiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Bioinformatics
Subjects:
group B Streptococcus
polymorphic mutation
pooled sample
dominant lineage
colonization
Online Access:https://www.frontiersin.org/articles/10.3389/fbinf.2022.813599/full

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https://www.frontiersin.org/articles/10.3389/fbinf.2022.813599/full

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