CXCL10 Signaling Contributes to the Pathogenesis of Arthritogenic Alphaviruses

Emerging and re-emerging arthritogenic alphaviruses, such as Chikungunya virus (CHIKV) and O’nyong nyong virus, cause acute and chronic crippling arthralgia associated with inflammatory immune responses. Approximately 50% of CHIKV-infected patients suffer from rheumatic manifestations that last 6 mo...

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Bibliographic Details
Main Authors: Tao Lin, Tingting Geng, Andrew G. Harrison, Duomeng Yang, Anthony T. Vella, Erol Fikrig, Penghua Wang
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/12/11/1252