Reciprocal discoidin domain receptor signaling strengthens integrin adhesion to connect adjacent tissues

Reciprocal discoidin domain receptor signaling strengthens integrin adhesion to connect adjacent tissues

Separate tissues connect through adjoining basement membranes to carry out molecular barrier, exchange, and organ support functions. Cell adhesion at these connections must be robust and balanced to withstand independent tissue movement. Yet, how cells achieve synchronized adhesion to connect tissue...

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Bibliographic Details
Main Authors: Kieop Park, Ranjay Jayadev, Sara G Payne, Isabel W Kenny-Ganzert, Qiuyi Chi, Daniel S Costa, William Ramos-Lewis, Siddharthan B Thendral, David R Sherwood
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-07-01
Series:eLife
Subjects:
type IV collagen
discoidin domain receptor
integrin
endocytosis
tissue connection
basement membrane
Online Access:https://elifesciences.org/articles/87037

Internet

https://elifesciences.org/articles/87037

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