Investigation of toxic factors affecting cells of rat brains exposed to 3-methylcatechol

Investigation of toxic factors affecting cells of rat brains exposed to 3-methylcatechol

The aim of this work was to study the effects of 3MC on the peroxidation of biomolecules in nuclear fractions and nonsynaptic mitochondrial respiration in organelles obtained from rat brains. The cytotoxicity towards rat primary astrocytes in vitro was also tested. 3MC at 1mM oxidized consuming oxyg...

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Bibliographic Details
Main Authors: George Emílio Sampaio Barreto, Elineusa Silva de Oliveira, Flávio Augusto Guerreiro Aragão de Villar, Gleide Souza dos Santos, Rute Maria Ferreira Lima, Silvia Lima Costa, Maria de Fátima Dias Costa, Eryvaldo Sócrates Tabosa Egito, Ramon Santos El-Bachá
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2007-09-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Astrocytes
brain
cytotoxicity
3-methylcatechol
peroxidation
respiration
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000500012

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000500012

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