Formulation and Evaluation of Self-Nanoemulsifying Drug Delivery System Derived Tablet Containing Sertraline

Formulation and Evaluation of Self-Nanoemulsifying Drug Delivery System Derived Tablet Containing Sertraline

Being a biopharmaceutics classification system class II drug, the absorption of sertraline from the gut is mainly limited by its poor aqueous solubility. The objective of this investigation was to improve the solubility of sertraline utilizing self-nanoemulsifying drug delivery systems (SNEDDS) and...

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Bibliographic Details
Main Authors: Anroop B. Nair, Bhavna Singh, Jigar Shah, Shery Jacob, Bandar Aldhubiab, Nagaraja Sreeharsha, Mohamed A. Morsy, Katharigatta N. Venugopala, Mahesh Attimarad, Pottathil Shinu
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Pharmaceutics
Subjects:
self-nanoemulsifying tablets
nanoemulsion
full factorial design
sertraline
pharmacokinetics
bioavailability
Online Access:https://www.mdpi.com/1999-4923/14/2/336

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https://www.mdpi.com/1999-4923/14/2/336

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