Assembling structurally customizable synthetic carriers of siRNA through thermodynamically self-regulated process
This study demonstrates that our previously reported polywraplex, a synthetic siRNA carrier consisting of a uni-molecular polyplex core of customizable size and a self-assembled tri-block copolymer envelop, may be constructed using dendrimers as the crosslinking junctions. Replacing the branched low...
Main Authors: | Guang Bai, Tong Xue, Xiaotao Dong, Uday Kumar Chinta, Jia Feng, Tuo Jin, Fei Wu |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-05-01
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Series: | Asian Journal of Pharmaceutical Sciences |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1818087618311577 |
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