Molecular Changes in Retinoblastoma beyond <i>RB1</i>: Findings from Next-Generation Sequencing

Molecular Changes in Retinoblastoma beyond <i>RB1</i>: Findings from Next-Generation Sequencing

This investigation uses hybridization capture-based next-generation sequencing to deepen our understanding of genetics that underlie retinoblastoma. Eighty-three enucleated retinoblastoma specimens were evaluated using a MSK-IMPACT clinical next-generation sequencing panel to evaluate both somatic a...

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Bibliographic Details
Main Authors: Jasmine H. Francis, Allison L. Richards, Diana L. Mandelker, Michael F. Berger, Michael F. Walsh, Ira J. Dunkel, Mark T. A. Donoghue, David H. Abramson
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
retinoblastoma
vitreous seeds
BCOR
next-generation sequencing
copy number variations
Online Access:https://www.mdpi.com/2072-6694/13/1/149

Internet

https://www.mdpi.com/2072-6694/13/1/149

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