Molecular signatures of proliferation and quiescence in hematopoietic stem cells.

Stem cells resident in adult tissues are principally quiescent, yet harbor enormous capacity for proliferation to achieve self renewal and to replenish their tissue constituents. Although a single hematopoietic stem cell (HSC) can generate sufficient primitive progeny to repopulate many recipients,...

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Bibliographic Details
Main Authors: Teresa A Venezia, Akil A Merchant, Carlos A Ramos, Nathan L Whitehouse, Andrew S Young, Chad A Shaw, Margaret A Goodell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2004-10-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.0020301