Diosgenyl 2-amino-2-deoxy-β-D-galactopyranoside: synthesis, derivatives and antimicrobial activity

Diosgenyl 2-amino-2-deoxy-β-D-galactopyranoside: synthesis, derivatives and antimicrobial activity

The synthesis of diosgenyl 2-amino-2-deoxy-β-D-galactopyranoside is presented for the first time. This synthetic saponin was transformed into its hydrochloride as well as N-acyl, 2-ureido, N-alkyl, and N,N-dialkyl derivatives. Antifungal and antibacterial studies show that some of the obtained compo...

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Bibliographic Details
Main Authors: Henryk Myszka, Patrycja Sokołowska, Agnieszka Cieślińska, Andrzej Nowacki, Maciej Jaśkiewicz, Wojciech Kamysz, Beata Liberek
Format: Article
Language:English
Published: Beilstein-Institut 2017-11-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
antimicrobial activities
D-galactosamine
diosgenin
glycosylation
saponin
tetrachlorophthalimido derivatives
Online Access:https://doi.org/10.3762/bjoc.13.227

Internet

https://doi.org/10.3762/bjoc.13.227

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