Phenotypic effects of mutations observed in the neuraminidase of human origin H5N1 influenza A viruses.

Phenotypic effects of mutations observed in the neuraminidase of human origin H5N1 influenza A viruses.

Global spread and regional endemicity of H5Nx Goose/Guangdong avian influenza viruses (AIV) pose a continuous threat for poultry production and zoonotic, potentially pre-pandemic, transmission to humans. Little is known about the role of mutations in the viral neuraminidase (NA) that accompanied bir...

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Bibliographic Details
Main Authors: David Scheibner, Ahmed H Salaheldin, Ola Bagato, Luca M Zaeck, Ahmed Mostafa, Ulrike Blohm, Christin Müller, Ahmed F Eweas, Kati Franzke, Axel Karger, Alexander Schäfer, Marcel Gischke, Donata Hoffmann, Solène Lerolle, Xuguang Li, Hatem S Abd El-Hamid, Jutta Veits, Angele Breithaupt, Geert-Jan Boons, Mikhail Matrosovich, Stefan Finke, Stephan Pleschka, Thomas C Mettenleiter, Robert P de Vries, Elsayed M Abdelwhab
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1011135

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https://doi.org/10.1371/journal.ppat.1011135

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