Phenotypic effects of mutations observed in the neuraminidase of human origin H5N1 influenza A viruses.
Global spread and regional endemicity of H5Nx Goose/Guangdong avian influenza viruses (AIV) pose a continuous threat for poultry production and zoonotic, potentially pre-pandemic, transmission to humans. Little is known about the role of mutations in the viral neuraminidase (NA) that accompanied bir...
Main Authors: | David Scheibner, Ahmed H Salaheldin, Ola Bagato, Luca M Zaeck, Ahmed Mostafa, Ulrike Blohm, Christin Müller, Ahmed F Eweas, Kati Franzke, Axel Karger, Alexander Schäfer, Marcel Gischke, Donata Hoffmann, Solène Lerolle, Xuguang Li, Hatem S Abd El-Hamid, Jutta Veits, Angele Breithaupt, Geert-Jan Boons, Mikhail Matrosovich, Stefan Finke, Stephan Pleschka, Thomas C Mettenleiter, Robert P de Vries, Elsayed M Abdelwhab |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2023-02-01
|
Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.1011135 |
Similar Items
-
Impact of Mutations in the Hemagglutinin of H10N7 Viruses Isolated from Seals on Virus Replication in Avian and Human Cells
by: Anne Dittrich, et al.
Published: (2018-02-01) -
Light Sheet Microscopy-Assisted 3D Analysis of SARS-CoV-2 Infection in the Respiratory Tract of the Ferret Model
by: Luca M. Zaeck, et al.
Published: (2021-03-01) -
Insertion of Basic Amino Acids in the Hemagglutinin Cleavage Site of H4N2 Avian Influenza Virus (AIV)—Reduced Virus Fitness in Chickens is Restored by Reassortment with Highly Pathogenic H5N1 AIV
by: Marcel Gischke, et al.
Published: (2020-03-01) -
The role of PB1-F2 in adaptation of high pathogenicity avian influenza virus H7N7 in chickens
by: Luise Hohensee, et al.
Published: (2024-01-01) -
Zoonotic Potential of Influenza A Viruses: A Comprehensive Overview
by: Ahmed Mostafa, et al.
Published: (2018-09-01)