Dynamically changing extracellular matrix stiffness drives Schwann cell phenotype

Dynamically changing extracellular matrix stiffness drives Schwann cell phenotype

Schwann cells (SCs) hold key roles in axonal function and maintenance in the peripheral nervous system (PNS) and are a critical component to the regeneration process following trauma. Following PNS trauma, SCs respond to both physical and chemical signals to modify phenotype and assist in the regene...

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Bibliographic Details
Main Authors: Alyssa Montgomery, Jennifer Westphal, Andrew E. Bryan, Greg M. Harris
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Matrix Biology Plus
Subjects:
Biomaterials
PNS injury
Schwann cell
Fibrosis
Extracellular matrix
Mechanotransduction
Online Access:http://www.sciencedirect.com/science/article/pii/S2590028524000279

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http://www.sciencedirect.com/science/article/pii/S2590028524000279

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