Fangchinoline induces antiviral response by suppressing STING degradation

Fangchinoline induces antiviral response by suppressing STING degradation

The stimulator of interferon genes (STING), an integral adaptor protein in the DNA-sensing pathway, plays a pivotal role in the innate immune response against infections. Additionally, it presents a valuable therapeutic target for infectious diseases and cancer. We observed that fangchinoline (Fan),...

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Bibliografiske detaljer
Main Authors: Jinyong Wang, Fang Xie, Xin Jia, Xuejiao Wang, Lingdong Kong, Yiying Li, Xue Liang, Meiqi Zhang, Yuting He, Wandi Feng, Tong Luo, Yao Wang, Anlong Xu
Format: Article
Sprog:English
Udgivet: Elsevier 2024-06-01
Serier:Journal of Pharmaceutical Analysis
Fag:
Fangchinoline
Virus
Type I interferons
Stimulator of interferon genes
Protein degradation
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http://www.sciencedirect.com/science/article/pii/S2095177924000698

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