Mitochondrial p38 Mitogen-Activated Protein Kinase: Insights into Its Regulation of and Role in LONP1-Deficient Nematodes

Mitochondrial p38 Mitogen-Activated Protein Kinase: Insights into Its Regulation of and Role in LONP1-Deficient Nematodes

p38 Mitogen-Activated Protein Kinase (MAPK) cascades are central regulators of numerous physiological cellular processes, including stress response signaling. In <i>C. elegans</i>, mitochondrial dysfunction activates a PMK-3/p38 MAPK signaling pathway (MAPK<sup>mt</sup>), but...

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Bibliographic Details
Main Authors: Eirini Taouktsi, Eleni Kyriakou, Evangelia Voulgaraki, Dimitris Verganelakis, Stefania Krokou, Stamatis Rigas, Gerassimos E. Voutsinas, Popi Syntichaki
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:International Journal of Molecular Sciences
Subjects:
mitochondria
ageing
heat stress response
<i>C. elegans</i>
LONP-1
PMK-3
Online Access:https://www.mdpi.com/1422-0067/24/24/17209

Internet

https://www.mdpi.com/1422-0067/24/24/17209

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