Full small molecule conversion of human fibroblasts to neuroectodermal cells via a cocktail of Dorsomorphin and Trichostatin A

Full small molecule conversion of human fibroblasts to neuroectodermal cells via a cocktail of Dorsomorphin and Trichostatin A

A revolutionary new approach to produce efficient cells is to induce transdifferentiation to make it conventional in therapeutic strategies. In this paper, we describe a brief cocktail of small molecules including Dorsomorphin (DSM) and Trichostatin A (TSA) to produce safe neuroectodermal cells as a...

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Bibliographic Details
Main Authors: Samaneh Sadat Hosseini Farahabadi, Kamran Ghaedi, Alireza Shoaraye-nejati, Mohammad-Hossein Nasr-Esfahani
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Regenerative Therapy
Subjects:
Fibroblast
Neuroectodermal cell
Small molecules
Transdifferentiation
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320420300511

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http://www.sciencedirect.com/science/article/pii/S2352320420300511

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