Exosomes/miRNAs as mediating cell-based therapy of stroke

Exosomes/miRNAs as mediating cell-based therapy of stroke

Cell-based therapy, e.g., multipotent mesenchymal stromal cell (MSC) treatment, shows promise for the treatment of various diseases. The strong paracrine capacity of these cells and not their differentiation capacity, is the principal mechanism of therapeutic action. MSCs robustly release exosomes,...

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Bibliographic Details
Main Authors: Hongqi eXin, Yi eLi, Michael eChopp
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Stroke
exosome
cell-based therapy
multipotent mesenchymal stromal cell (MSC)
microRNAs (miRNAs)
bio-information transfer
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00377/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00377/full

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